빠른 메뉴



Biomedical Optics and Photomedicine Lab.


Research

Biomedical Optics and Photomedicine is an interdisciplinary research area, which utilizes diverse optical technologies to address challenging medical problems. Novel optical technologies continue to advance at a rapid rate, enabling early diagnosis, screening, monitoring, and treatment of various medical conditions virtually in all medical fields ranging from ophthalmology and dermatology to gastroenterology and cardiology.

Research interest at the Biomedical Optics and Photomedicine Lab. focuses on the development of new optical imaging techniques, and its application to medical problems, in order to improve the patient care. We work on developing novel optical instrumentations and methods based on advanced optical techniques, such as optical frequency domain imaging, optical coherence tomography, confocal microscopy, and fluorescence molecular imaging. Specifically, our focus in this area is on the development of optical imaging catheters and endoscopic probes using optical fibers and micro optics.

Cardiovascular disease remains the leading cause of death in many developed countries. Advanced imaging catheters may open up new opportunities for investigating coronary artery disease by providing comprehensive information associated with high-risk plaques in vivo. Diagnosis, screening, and monitoring esophageal diseases involve a biopsy of suspicious tissue. High-resolution microendoscopy could provide a less-invasive method for monitoring and screening patients that does not require the excisional biopsy.

We are putting a lot of effort into developing novel optical instrumentations and translating these new technologies into preclinical and clinical studies. Our researches will improve patient care by providing advanced diagnostic and therapeutic methods.

Multimodality imaging

  • Optical coherence tomography (OCT)
  • Optical frequency domain imaging (OFDI)
  • Near infrared fluorescence (NIRF) molecular imaging
  • Multimodality OFDI-NIRF imaging catheter with activatable nano-probe
  • Balloon catheter for esophageal imaging using OFDI

Multimodality imaging

Advanced imaging methods

  • Spectrally-encoded confocal microscopy (SECM)
  • Endoscopic SECM imaging probe
  • High-sensitive molecular imaging probe
  • Stimulated emission depletion (STED) microscopy with ultra-high resolution

Advanced imaging methods

Cardiovascular disease

  • Intravascular optical imaging catheter based on optical fibers
  • Multimodality imaging catheter using specialized optical fibers
  • Imaging of inflammatory cells and enzymatic activity in high-risk atherosclerotic plaque
  • Monitoring therapeutic responses for cardiovascular disease

Cardiovascular disease

Esophageal disease

  • Diagnosis of Barrett’s esophagus using OFDI and OCT
  • Diagnosis of Barrett’s esophagus and eosinophilic esophagitis using SECM
  • Study on diagnosis of various esophageal diseases using multimodality imaging catheters

Esophageal disease


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BOP Lab., 108 R&D Building, Dept. of Biomedical Engineering, Hanyang University,
222 Wangsimni-ro, Seongdong-gu, Seoul, 133-791, Korea / Tel: +82-2-2220-4328, Fax: +82-2-2296-5943
홈페이지 책임자: 유홍기 교수 (hyoo (at) hanyang.ac.kr) / 홈페이지 담당자: 남형수 (pacific (at) bme.hanyang.ac.kr)